And they're using award winning wines and food, nature, and the relatively low profile of the region as their biggest drawcards.
Tahbilk Winery and Mitchelton Wines, near Nagambie, and Fowles Wine, at Avenel, have been hit hard by border closures and the 'ring of steel' but have joined forces to rebuild tourism now travelling is becoming more accessible.
"Each winery is completely different," Fowles Wine owner Matt Fowles said.
"Yet, by coming together, we offer the chance for guests to experience the best of the Victorian wine industry in a day.
"This is a great opportunity for people who want real, authentic experiences."
Like most businesses in the region, Tahbilk, Fowles, and Mitchelton depend upon holiday makers and day-trippers using the Hume Highway, which completely dried up as a source of tourism in 2020.
But now the renowned shiraz and riesling producers are fighting back, using the region’s natural hidden gems, and relatively low tourism profile, as part of a new campaign to secure their share of Victoria’s $10 billion regional tourism market.
"Relatively little-known wine regions and townships, like nearby Nagambie and Avenel, now have a fighting chance to compete with better-known visitor destinations because of the virus," Mr Fowles said.
Tahbilk chief executive officer Alister Purbrick said there were about 4.4 million people visiting and spending money in regional Victoria every month in 2019.
"That's a lot of visitors, even before the pandemic begun, and that gives us a lot of heart to make a serious comeback from the ravage of this pandemic," he said.
With Victoria’s regional tourism boom expected to go deep into next year, Mr Purbrick said it made sense for the three wineries to band together to offer an attractive alternative to the regular touristy spots.
"In the coming months, we expect to see a surge in visitors from Melbourne, within the region, and even interstate, looking for places to visit and explore, which are different, unexpected, and safe," Mr Purbrick said.
"People will still want to have a great food and wine experience in a beautiful regional setting.
"But, post-lockdown, they will also want to be able to stretch out, breathe, feel safe, and be totally free from the hassle of queues and crowds, which is exactly what we are offering."
Andrew Santarossa, who is the chief winemaker at Mitchelton, said the Take Nature's Road Trip campaign exploited the fact the region is not always top-of-mind, or on the ‘map’, for most day-trippers.
“For us, this has become one of our greatest strengths as we don't have the same crowds, or traffic problems, which other more frequented regional wine destinations are likely to encounter this coming summer.
"But what we do have is an amazing natural setting boasting some of Victoria's best wineries and dining, wide-open spaces, the Goulburn River and ranges, bush trails and billabongs, and friendly smiles."
Take Nature’s Road Trip advertising will start appearing on main arterial billboards, social media platforms, and in the region's local townships during December.