Prime Minister Anthony Albanese wants to retain majority government after next year's national vote, despite opinion polls showing Labor is behind the coalition.
The seat of Braddon in north-west Tasmania is held by Liberal Gavin Pearce on an eight per cent margin.
It's seen as a key seat for Labor, given Mr Pearce will not stand for re-election.
"I'm confident, I'm about (a) majority Labor government," Mr Albanese told reporters in Devonport on Tuesday when asked about the prospects of Labor losing seats.
Senator Urquhart was first elected to represent the Apple Isle in 2010 and was re-elected in 2016 and 2022.
Her current term expires in 2028, meaning Labor will need to appoint a replacement to fill the vacancy in the upper house.
"I will fight for the best for this region, that's my priority," Senator Urquhart said alongside Mr Albanese.
Mr Albanese will soon announce Labor's candidate for the neighbouring seat of Bass, held by Liberal MP Bridget Archer on a slim 1.4 per cent margin.
Labor is also looking to sandbag the adjoining seat of Lyons, which it holds by less than one per cent.
All three Tasmanian seats defied the national trend and swung towards the Liberal Party in the 2022 federal election.
Agriculture, Fisheries and Forestry Minister Julie Collins holds the Tasmanian seat of Franklin by almost 14 per cent.
But she took a sizeable 7.3 per cent hit to her primary vote in 2022, before surviving with a small 1.5 per cent swing towards her after preferences.
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